Msp1 Clears Mistargeted Proteins by Facilitating Their Transfer from Mitochondria to the ER
نویسندگان
چکیده
منابع مشابه
Msp1: patrolling mitochondria for lost proteins.
Intracellular protein localization is critical for establishing organelle identity, avoiding inappropriate interactions, and maintaining cellular function. An emerging mechanism for ensuring high-fidelity protein localization is the selective destruction of mislocalized copies. Two new papers find that the mitochondrial outer membrane is kept free of mislocalized proteins by Msp1 (Chen et al, 2...
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ژورنال
عنوان ژورنال: Molecular Cell
سال: 2019
ISSN: 1097-2765
DOI: 10.1016/j.molcel.2019.07.006